Abstract
Keywords
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to Clinical Colorectal CancerReferences
- Pancreatic cancer: a review.JAMA. 2021; 326: 851-862https://doi.org/10.1001/jama.2021.13027
- Cancer statistics, 2021.CA Cancer J Clin. 2021; 71: 7-33
- Correlation of clinical stage and performance status with quality of life in patients seen in a pancreas multidisciplinary clinic.J Oncol Pract. 2015; 11: e216-e221https://doi.org/10.1200/JOP.2014.000976
- Symptom concerns and quality of life in hepatobiliary cancers.Oncol Nurs Forum. 2008; 35: E45-E52https://doi.org/10.1188/08.ONF.E45-E52
- Association between pancreatic cancer patients' perception of their care coordination and patient-reported and survival outcomes.Palliat Support Care. 2018; 16: 534-543https://doi.org/10.1017/S1478951517000608
- A qualitative investigation of the supportive care experiences of people living with pancreatic and oesophagogastric cancer.BMC Health Serv Res. 2022; 22: 213https://doi.org/10.1186/s12913-022-07625-y
- A myriad of symptoms: new approaches to optimizing palliative care of patients with advanced pancreatic cancer.Am Soc Clin Oncol Educ Book. 2012; : 243-248https://doi.org/10.14694/EdBook_AM.2012.32.15
- Symptom Management in Pancreatic Cancer.Curr Treat Options Oncol. 2021; 22: 8https://doi.org/10.1007/s11864-020-00801-4
Moffat GT, Epstein AS, O'Reilly EM. Pancreatic cancer-A disease in need: optimizing and integrating supportive care. Cancer. 2019;125:3927-35. doi: 10.1002/cncr.32423.
- Pancreatic cancer: best supportive care.Presse Med. 2019; 48: e175-e185https://doi.org/10.1016/j.lpm.2019.02.032
- The role of a symptom assessment tool in shaping patient-physician communication in palliative care.J Pain Symptom Manage. 2020; 59: 30-38https://doi.org/10.1016/j.jpainsymman.2019.08.024
- The edmonton symptom assessment system 25 years later: past, present, and future developments.J Pain Symptom Manage. 2017; 53: 630-643https://doi.org/10.1016/j.jpainsymman.2016.10.370
- Validation and application of a module of the M. D. Anderson Symptom Inventory for measuring multiple symptoms in patients with gastrointestinal cancer (the MDASI-GI).Cancer. 2010; 116: 2053-2063https://doi.org/10.1002/cncr.24920
- The memorial symptom assessment scale short form (MSAS-SF).Cancer. 2000; 89 (10.1002/1097-0142(20000901)89:5<1162::aid-cncr26>3.0.co;2-y): 1162-1171
- Development of a disease specific quality of life (QoL) questionnaire module to supplement the EORTC core cancer QoL questionnaire, the QLQ-C30 in patients with pancreatic cancer. EORTC Study Group on Quality of Life.Eur J Cancer. 1999; 35: 939-941https://doi.org/10.1016/s0959-8049(99)00047-7
- Measuring health-related quality of life in patients with hepatobiliary cancers: the functional assessment of cancer therapy-hepatobiliary questionnaire.J Clin Oncol. 2002; 20: 2229-2239https://doi.org/10.1200/JCO.2002.07.093
- Patient-reported outcome measures (PROMs) in pancreatic cancer: a systematic review.HPB (Oxford). 2020; 22: 187-203https://doi.org/10.1016/j.hpb.2019.09.002
- Landscape of health-related quality of life in patients with early-stage pancreatic cancer receiving adjuvant or neoadjuvant chemotherapy: a systematic literature review.Pancreas. 2020; 49: 393-407https://doi.org/10.1097/MPA.0000000000001507
- Gastrointestinal malignancies and supportive care trials: a snapshot of the last two decades.BMJ Support Palliat Care. 2022; 12: 42-45https://doi.org/10.1136/bmjspcare-2020-002538
- Symptom clusters in patients with pancreatic cancer undergoing surgical resection: part I.Oncol Nurs Forum. 2018; 45: E36-E52https://doi.org/10.1188/18.ONF.E36-E52
- Symptom clusters in patients with pancreatic cancer undergoing surgical resection: part II.Oncol Nurs Forum. 2018; 45: E53-E66https://doi.org/10.1188/18.ONF.E53-E66
- Malignant ascites symptom cluster in patients referred for paracentesis.Ann Surg Oncol. 2010 Feb; 17: 461-469https://doi.org/10.1245/s10434-009-0774-0
- Changes in the occurrence, severity, and distress of symptoms in patients with gastrointestinal cancers receiving chemotherapy.J Pain Symptom Manage. 2018; 55: 808-834https://doi.org/10.1016/j.jpainsymman.2017.10.004
- Symptom clusters in patients with gastrointestinal cancers using different dimensions of the symptom experience.J Pain Symptom Manage. 2019; 58: 224-234https://doi.org/10.1016/j.jpainsymman.2019.04.035
- Signs and symptoms of pancreatic cancer: a population-based case-control study in the San Francisco Bay area.Clin Gastroenterol Hepatol. 2004; 2: 510-517https://doi.org/10.1016/s1542-3565(04)00171-5
- Chart review of diagnostic methods, baseline characteristics and symptoms for European patients with pancreatic cancer.Future Oncol. 2021; 17: 1843-1854https://doi.org/10.2217/fon-2020-0749
- Population-level symptom assessment following pancreaticoduodenectomy for adenocarcinoma.JAMA Surg. 2019; 154e193348https://doi.org/10.1001/jamasurg.2019.3348
- Impact of pancreatectomy on long-term patient-reported symptoms and quality of life in recurrence-free survivors of pancreatic and periampullary neoplasms.J Surg Oncol. 2017; 115: 144-150https://doi.org/10.1002/jso.24499
- Symptom burden of nonresected pancreatic adenocarcinoma: an analysis of 10,753 patient-reported outcome assessments.Pancreas. 2020; 49: 1083-1089https://doi.org/10.1097/MPA.0000000000001629
- The symptom experience of patients with advanced pancreatic cancer: an integrative review.Cancer Nurs. 2018; 41: 33-44https://doi.org/10.1097/NCC.0000000000000463
- The FOCCUS study: a prospective evaluation of the frequency, severity and treatable causes of gastrointestinal symptoms during and after chemotherapy.Support Care Cancer. 2021; 29: 1443-1453https://doi.org/10.1007/s00520-020-05610-x
- Quality of life of patients with metastatic pancreatic adenocarcinoma initiating first-line chemotherapy in routine practice.BMC Palliat Care. 2020; 19: 103https://doi.org/10.1186/s12904-020-00610-4
- Index symptoms and prognosis awareness of patients with pancreatic cancer: a multi-site palliative care collaborative.J Palliat Care. 2021; 8258597211001596https://doi.org/10.1177/08258597211001596
- Symptom trajectories and predictors of severe symptoms in pancreatic adenocarcinoma at the end-of-life: a population based analysis of 2,538 patients.HPB (Oxford). 2019; 21: 1744-1752https://doi.org/10.1016/j.hpb.2019.04.016
- Critical changes in hypothalamic gene networks in response to pancreatic cancer as found by single-cell RNA sequencing.Mol Metab. 2022; 58101441https://doi.org/10.1016/j.molmet.2022.101441
- Emerging signaling mediators in the anorexia-cachexia syndrome of cancer.Trends Cancer. 2022; 8: 397-403https://doi.org/10.1016/j.trecan.2022.01.004
- Lipocalin 2 mediates appetite suppression during pancreatic cancer cachexia.Nat Commun. 2021; 12: 2057https://doi.org/10.1038/s41467-021-22361-3
- Symptom experiences in patients with advanced pancreatic cancer as reported during healthcare encounters.Eur J Cancer Care (Engl). 2018; 27: e12838https://doi.org/10.1111/ecc.12838
- Psychosocial consequences of a reduced ability to eat for patients with cancer and their informal caregivers: a qualitative study.Eur J Oncol Nurs. 2020; 49101838https://doi.org/10.1016/j.ejon.2020.101838
- Patients with cancer experience high impact of emotional consequences of reduced ability to eat: a cross sectional survey study.Eur J Cancer Care (Engl). 2022; 31: e13595https://doi.org/10.1111/ecc.13595
- Comprehensive validation of the functional assessment of anorexia/cachexia therapy (FAACT) anorexia/cachexia subscale (A/CS) in lung cancer patients with involuntary weight loss.Qual Life Res. 2019; 28: 1641-1653https://doi.org/10.1007/s11136-019-02135-7
- Diet and nutrition advice after a solid tumor diagnosis.JCO Oncol Pract. 2021; 17: e982-e991https://doi.org/10.1200/OP.20.00685
- Experiences of patients with cancer with information and support for psychosocial consequences of reduced ability to eat: a qualitative interview study.Support Care Cancer. 2021; 29: 6343-6352https://doi.org/10.1007/s00520-021-06217-6
NCCN Guidelines Version 1.2022 Palliative Care https://www.nccn.org/professionals/physician_gls/pdf/palliative.pdf. Accessed: August 28, 2022.
- Cancer cachexia in adult patients: ESMO Clinical Practice Guidelines☆.ESMO Open. 2021; 6100092https://doi.org/10.1016/j.esmoop.2021.100092
- A hunger for hunger: a review of palliative therapies for cancer-associated anorexia.Ann Palliat Med. 2019; 8: 50-58https://doi.org/10.21037/apm.2018.05.08
- A multicenter, open-label, single-arm study of anamorelin (ONO-7643) in advanced gastrointestinal cancer patients with cancer cachexia.Cancer. 2019; 125: 4294-4302https://doi.org/10.1002/cncr.32406
Sexton M, Garcia JM, Jatoi A, Clark CS, Wallace MS. The management of cancer symptoms and treatment-induced side effects with cannabis or cannabinoids. J Natl Cancer Inst Monogr 2021;2021:86-98. doi: 10.1093/jncimonographs/lgab011.
- Clinical outcomes and contributors to weight loss in a cancer cachexia clinic.J Palliat Med. 2011; 14: 1004-1008https://doi.org/10.1089/jpm.2011.0098
- Chronic constipation: a survey of the patient perspective.Aliment Pharmacol Ther. 2007; 25: 599-608https://doi.org/10.1111/j.1365-2036.2006.03238.x
- Validity and reliability of the constipation assessment scale.Cancer Nurs. 1989; 12: 183-188https://doi.org/10.1097/00002820-198906000-00012
- Modified Edmonton Symptom Assessment System including constipation and sleep: validation in outpatients with cancer.J Pain Symptom Manage. 2015; 49: 945-952https://doi.org/10.1016/j.jpainsymman.2014.10.013
- Assessment of constipation in patients with cancer.J Adv Pract Oncol. 2016; 7: 457-462
- Metrics Used to Quantify Fecal Incontinence and Constipation.Clin Colon Rectal Surg. 2021; 34: 5-14https://doi.org/10.1055/s-0040-1714245
- MASCC recommendations on the management of constipation in patients with advanced cancer.Support Care Cancer. 2020; 28: 23-33https://doi.org/10.1007/s00520-019-05016-4
- Diagnosis, assessment and management of constipation in advanced cancer: ESMO Clinical Practice Guidelines.Ann Oncol. 2018; 29: iv111-iv125https://doi.org/10.1093/annonc/mdy148
PAL 17. Available at: https://www.nccn.org/professionals/physician_gls/pdf/palliative.pdf. Accessed: August 28, 2022.
PAL-18. Available at: https://www.nccn.org/professionals/physician_gls/pdf/palliative.pdf. Accessed: August 28, 2022.
- Electronic address: [email protected] Diarrhoea in adult cancer patients: ESMO clinical practice guidelines.Ann Oncol. 2018; 29 (Suppl): iv126-iv142https://doi.org/10.1093/annonc/mdy145
- Olanzapine for the treatment of advanced cancer-related chronic nausea and/or vomiting: a randomized pilot trial.JAMA Oncol. 2020; 6: 895-899https://doi.org/10.1001/jamaoncol.2020.1052
- Methotrimeprazine versus haloperidol in palliative care patients with cancer-related nausea: a randomised, double-blind controlled trial.BMJ Open. 2019; 9e029942https://doi.org/10.1136/bmjopen-2019-029942
- A randomized open-label study of guideline-driven antiemetic therapy versus single agent antiemetic therapy in patients with advanced cancer and nausea not related to anticancer treatment.BMC Cancer. 2018; 18: 510https://doi.org/10.1186/s12885-018-4404-8
- MASCC antiemetics in advanced cancer updated guideline.Support Care Cancer. 2021; 29: 8097-8107https://doi.org/10.1007/s00520-021-06437-w
PAL-15. Available at: https://www.nccn.org/professionals/physician_gls/pdf/palliative.pdf. Accessed: August 28, 2022.
- Acupuncture as a tool to reduce nausea in terminally ill patients.Scand J Caring Sci. 2021; https://doi.org/10.1111/scs.12991
- Medical management of malignant bowel obstruction in patients with advanced cancer: 2021 MASCC guideline update.Support Care Cancer. 2021; 29: 8089-8096https://doi.org/10.1007/s00520-021-06438-9
- MASCC multidisciplinary evidence-based recommendations for the management of malignant bowel obstruction in advanced cancer.Support Care Cancer. 2022; 30: 4711-4728https://doi.org/10.1007/s00520-022-06889-8
- Somatostatin analogues compared with placebo and other pharmacologic agents in the management of symptoms of inoperable malignant bowel obstruction: a systematic review.J Pain Symptom Manage. 2016; 52 (901-19.e1)https://doi.org/10.1016/j.jpainsymman.2016.05.032
- Nausea and vomiting in advanced cancer.Curr Treat Options Oncol. 2020; 21: 14https://doi.org/10.1007/s11864-020-0704-8
- My love is hurting: the meaning spouses attribute to their loved ones' pain during palliative care.J Palliat Care. 2003; 19: 87-94
- Pain syndromes and pharmacologic management of pancreatic cancer pain.J Pain Symptom Manage. 1988; 3: 176-187https://doi.org/10.1016/0885-3924(88)90028-0
- AAPT diagnostic criteria for chronic cancer pain conditions.J Pain. 2017; 18: 233-246https://doi.org/10.1016/j.jpain.2016.10.020
- Pancreatic neuropathy and neuropathic pain–a comprehensive pathomorphological study of 546 cases.Gastroenterology. 2009; 136: 177-186.e1https://doi.org/10.1053/j.gastro.2008.09.029
- Perineural invasion and associated pain transmission in pancreatic cancer.Cancers (Basel). 2021; 13: 4594https://doi.org/10.3390/cancers13184594
- Abdominal pain in patients with resectable pancreatic cancer with reference to clinicopathologic findings.Pancreas. 2001; 22: 279-284https://doi.org/10.1097/00006676-200104000-00009
- Prospective evaluation of associations between cancer-related pain and perineural invasion in patients with resectable pancreatic adenocarcinoma.J Gastrointest Surg. 2017; 21: 1658-1665https://doi.org/10.1007/s11605-017-3513-z
- Pancreatic pain-knowledge gaps and research opportunities in children and adults: summary of a national institute of diabetes and digestive and kidney diseases workshop.Pancreas. 2021; 50: 906-915https://doi.org/10.1097/MPA.0000000000001899
- Chronic cancer pain syndromes.in: Cherny NI Fallon MT Kasa S Portenoy RK Currow DC Oxford Textbook of Palliative Medicine. 6th edition. Oxford University Press, New York, NY2021: 345-363 (Chapter 7.4)
- Pain and depression in patients with newly diagnosed pancreas cancer.J Clin Oncol. 1995; 13: 748-755https://doi.org/10.1200/JCO.1995.13.3.748
- A preoperative score to predict early death after pancreatic cancer resection.Dig Liver Dis. 2017; 49: 1050-1056https://doi.org/10.1016/j.dld.2017.06.012
- Pooling of prognostic studies in cancer of the pancreatic head and periampullary region: the Triple-P study.Triple-P Study Group Eur J Surg. 2000; 166: 706-712https://doi.org/10.1080/110241500750008466
- Cancer pain self-management in the context of a national opioid epidemic: experiences of patients with advanced cancer using opioids.Cancer. 2021; 127: 3239-3245https://doi.org/10.1002/cncr.33532
- An interdisciplinary approach to metastatic pancreatic cancer and comorbid opioid use disorder treatment within a VA health care system.Fed Pract. 2021; 38 (Suppl): S66-S71https://doi.org/10.12788/fp.0160
- Palliative care's role managing cancer pain during the opioid crisis: a qualitative study of patients, caregivers, and clinicians.J Pain Symptom Manage. 2020; 60: 1127-1135https://doi.org/10.1016/j.jpainsymman.2020.06.039
- Expert panel consensus on management of advanced cancer-related pain in individuals with opioid use disorder.JAMA Netw Open. 2021; 4e2139968https://doi.org/10.1001/jamanetworkopen.2021.39968
- Consensus-based guidance on opioid management in individuals with advanced cancer-related pain and opioid misuse or use disorder.JAMA Oncol. 2022; e222191https://doi.org/10.1001/jamaoncol.2022.2191
- Nonopioid drug combinations for cancer pain: a systematic review.Pain Rep. 2021; 7: e995https://doi.org/10.1097/PR9.0000000000000995
- Patient experience and quality of life during neoadjuvant therapy for pancreatic cancer: a systematic review and study protocol.Support Care Cancer. 2021; 29: 3009-3016https://doi.org/10.1007/s00520-020-05813-2
- EFSUMB guidelines on interventional ultrasound (INVUS), Part V - EUS-guided therapeutic interventions (short version).Ultraschall Med. 2016; 37: 412-420https://doi.org/10.1055/s-0035-1553742
- Consensus guidelines on the optimal management in interventional EUS procedures: results from the Asian EUS group RAND/UCLA expert panel.Gut. 2018; 67: 1209-1228https://doi.org/10.1136/gutjnl-2017-314341
- Practice guidelines for endoscopic ultrasound-guided celiac plexus neurolysis.Endosc Ultrasound. 2017; 6: 369-375
- Splanchnicectomy for pancreatic cancer pain.Biomed Res Int. 2014; 2014941726https://doi.org/10.1155/2014/941726
- Pancreatic cancer related pain: review of pathophysiology and intrathecal drug delivery systems for pain management.Pain Physician. 2021; 24: E583-E594
- Pain relief after a short course of palliative radiotherapy in pancreatic cancer, the Academic Medical Center (AMC) experience.Acta Oncol. 2018; 57: 697-700https://doi.org/10.1080/0284186X.2017.1400692
- Pain relief after stereotactic radiotherapy of pancreatic adenocarcinoma: an updated systematic review.Curr Oncol. 2022; 29: 2616-2629https://doi.org/10.3390/curroncol29040214
- Psychological and behavioral approaches to cancer pain management.J Clin Oncol. 2014; 32: 1703-1711https://doi.org/10.1200/JCO.2013.54.4825
- The biopsychosocial model in cancer pain.Curr Opin Support Palliat Care. 2014; 8: 117-123https://doi.org/10.1097/SPC.0000000000000046
- Enhancing meaning in the face of advanced cancer and pain: qualitative evaluation of a meaning-centered psychosocial pain management intervention.Palliat Support Care. 2020; 18: 263-270https://doi.org/10.1017/S1478951520000115
- Randomized clinical trial of the effectiveness of a self-care intervention to improve cancer pain management.J Clin Oncol. 2004; 22: 1713-1720https://doi.org/10.1200/JCO.2004.06.140
- A randomized, clinical trial of education or motivational-interviewing-based coaching compared to usual care to improve cancer pain management.Oncol Nurs Forum. 2012; 39: 39-49https://doi.org/10.1188/12.ONF.39-49
- Meta-analysis of psychosocial interventions to reduce pain in patients with cancer.J Clin Oncol. 2012; 30: 539-547https://doi.org/10.1200/JCO.2011.37.0437
- Caregiver-guided pain coping skills training for patients with advanced cancer: results from a randomized clinical trial.Palliat Med. 2021; 35: 952-961https://doi.org/10.1177/02692163211004216
- Acupuncture and Derived therapies for pain in palliative cancer management: systematic review and meta-analysis based on single-arm and controlled trials.J Palliat Med. 2021; 24: 1078-1099https://doi.org/10.1089/jpm.2020.0405
- Acupuncture for palliative cancer pain management: systematic review.BMJ Support Palliat Care. 2021; 11: 264-270https://doi.org/10.1136/bmjspcare-2020-002638
- Integrative medicine therapies for pain management in cancer patients.Cancer J. 2019; 25: 343-348https://doi.org/10.1097/PPO.0000000000000399
- Cannabinoids, cannabis, and cannabis-based medicine for pain management: a systematic review of randomised controlled trials.Pain. 2021; 162 (Suppl): S45-S66https://doi.org/10.1097/j.pain.0000000000001929
- Pancreas cancer-associated pain management.Oncologist. 2021; 26: e971-e982https://doi.org/10.1002/onco.13796
- Pathogenesis and treatment of pancreatic cancer related pain.Anticancer Res. 2020; 40: 1789-1796https://doi.org/10.21873/anticanres.14133
- Pain in pancreatic ductal adenocarcinoma: a multidisciplinary, International guideline for optimized management.Pancreatology. 2018; 18: 446-457https://doi.org/10.1016/j.pan.2018.04.008
- Chemotherapy-induced sarcopenia.Curr Treat Options Oncol. 2020; 21: 7https://doi.org/10.1007/s11864-019-0691-9
- Prevalence and survival impact of pretreatment cancer-associated weight loss: a tool for guiding early palliative care.J Oncol Pract. 2018; 14: e238-e250https://doi.org/10.1200/JOP.2017.025221
- Prevalence of malnutrition in patients at first medical oncology visit: the PreMiO study.Oncotarget. 2017; 8: 79884-79896https://doi.org/10.18632/oncotarget.20168
- Cachexia worsens prognosis in patients with resectable pancreatic cancer.J Gastrointest Surg. 2008; 12: 1193-1201https://doi.org/10.1007/s11605-008-0505-z
- Diagnostic criteria for the classification of cancer-associated weight loss.J Clin Oncol. 2015; 33: 90-99https://doi.org/10.1200/JCO.2014.56.1894
- Diagnostic criteria for cancer cachexia: reduced food intake and inflammation predict weight loss and survival in an international, multi-cohort analysis.J Cachexia Sarcopenia Muscle. 2021; 12: 1189-1202https://doi.org/10.1002/jcsm.12756
- Anthropometric changes in patients with pancreatic cancer undergoing preoperative therapy and pancreatoduodenectomy.J Gastrointest Surg. 2018; 22: 703-712https://doi.org/10.1007/s11605-017-3618-4
- Assessing nutritional status in cancer: role of the patient-generated subjective global assessment.Curr Opin Clin Nutr Metab Care. 2017; 20: 322-329https://doi.org/10.1097/MCO.0000000000000389
- Validation of the Malnutrition Universal Screening Tool (MUST) in cancer.Br J Nutr. 2012; 108: 343-348https://doi.org/10.1017/S000711451100571X
- Screening for undernutrition in geriatric practice: developing the short-form mini-nutritional assessment (MNA-SF).J Gerontol A Biol Sci Med Sci. 2001; 56: M366-M372https://doi.org/10.1093/gerona/56.6.m366
- Nutritional risk screening (NRS 2002): a new method based on an analysis of controlled clinical trials.Clin Nutr. 2003; 22: 321-336https://doi.org/10.1016/s0261-5614(02)00214-5
- Nutritional risk screening in cancer patients: the first step toward better clinical outcome.Front Nutr. 2021; 8603936https://doi.org/10.3389/fnut.2021.603936
- GLIM criteria for the diagnosis of malnutrition - a consensus report from the global clinical nutrition community.Clin Nutr. 2019; 38: 1-9https://doi.org/10.1016/j.clnu.2018.08.002
- Pancreas cancer-associated weight loss.Oncologist. 2019; 24: 691-701https://doi.org/10.1634/theoncologist.2018-0266
- ESPEN practical guideline: clinical nutrition in cancer.Clin Nutr. 2021; 40: 2898-2913https://doi.org/10.1016/j.clnu.2021.02.005
- Oral nutrition interventions in patients undergoing gastrointestinal surgery for cancer: a systematic literature review.Support Care Cancer. 2020; 28: 5673-5691https://doi.org/10.1007/s00520-020-05673-w
- Oral nutritional interventions in malnourished patients with cancer: a systematic review and meta-analysis.J Natl Cancer Inst. 2012; 104: 371-385https://doi.org/10.1093/jnci/djr556
- Systematic review and meta-analysis of the evidence for oral nutritional intervention on nutritional and clinical outcomes during chemo(radio)therapy: current evidence and guidance for design of future trials.Ann Oncol. 2018; 29: 1141-1153https://doi.org/10.1093/annonc/mdy114
- Clinical and economic value of oral nutrition supplements in patients with cancer: a position paper from the survivorship care and nutritional support working group of alliance against cancer.Support Care Cancer. 2022; https://doi.org/10.1007/s00520-022-07269-y
- Multinational Association of Supportive Care in Cancer (MASCC) expert opinion/guidance on the use of clinically assisted nutrition in patients with advanced cancer.Support Care Cancer. 2022; 30: 2983-2992https://doi.org/10.1007/s00520-021-06613-y
- The deliverability, acceptability, and perceived effect of the Macmillan approach to weight loss and eating difficulties: a phase II, cluster-randomized, exploratory trial of a psychosocial intervention for weight- and eating-related distress in people with advanced cancer.J Pain Symptom Manage. 2010; 40: 684-695https://doi.org/10.1016/j.jpainsymman.2010.02.015
- The effects of a family-centered psychosocial-based nutrition intervention in patients with advanced cancer: the PiCNIC2 pilot randomised controlled trial.Nutr J. 2021; 20: 2https://doi.org/10.1186/s12937-020-00657-2
- Management of cancer cachexia and guidelines implementation in a comprehensive cancer center: a physician-led cancer nutrition program adapted to the practices of a country.J Pain Symptom Manage. 2017; 54: 387-393.e3https://doi.org/10.1016/j.jpainsymman.2017.01.010
- From guidelines to clinical practice: a roadmap for oncologists for nutrition therapy for cancer patients.Ther Adv Med Oncol. 2019; 11https://doi.org/10.1177/1758835919880084
- Nutrition in pancreatic cancer: a review.Gastrointest Tumors. 2016; 2: 195-202https://doi.org/10.1159/000442873
- Nutritional interventions in pancreatic cancer: a systematic review.Cancers (Basel). 2022; 14: 2212https://doi.org/10.3390/cancers14092212
- Pancreas adenocarcinoma: ascites, clinical manifestations, and management implications.Clin Colorectal Cancer. 2016; 15: 360-368https://doi.org/10.1016/j.clcc.2016.04.014
- Therapeutic procedures for malignant ascites in a palliative care outpatient clinic.J Palliat Med. 2018; 21: 836-841https://doi.org/10.1089/jpm.2017.0616
- Validation of the edmonton symptom assessment system: ascites modification.J Pain Symptom Manage. 2018; 55: 1557-1563https://doi.org/10.1016/j.jpainsymman.2018.03.016
- The ability of existing questionnaires to measure symptom change after paracentesis for symptomatic ascites.Ann Surg Oncol. 2007; 14: 2348-2357https://doi.org/10.1245/s10434-007-9370-3
- Psychosocial impact of cancer cachexia.J Cachexia Sarcopenia Muscle. 2014; 5: 89-94https://doi.org/10.1007/s13539-014-0142-1
- Addressing unmet needs for people with cancer cachexia: recommendations from a multistakeholder workshop.J Cachexia Sarcopenia Muscle. 2022; 13: 1418-1425https://doi.org/10.1002/jcsm.12910
- A systematic review and thematic synthesis of quality of life in the informal carers of cancer patients with cachexia.Palliat Med. 2016; 30: 149-160https://doi.org/10.1177/0269216315588743
- Psychosocial effects of cancer cachexia: a systematic literature search and qualitative analysis.J Pain Symptom Manage. 2013; 46: 77-95https://doi.org/10.1016/j.jpainsymman.2012.06.020
- Barriers to cancer nutrition therapy: excess catabolism of muscle and adipose tissues induced by tumour products and chemotherapy.Proc Nutr Soc. 2018; 77: 394-402https://doi.org/10.1017/S0029665118000186
- Pancreatic cancer cachexia: three dimensions of a complex syndrome.Br J Cancer. 2021; 124: 1623-1636https://doi.org/10.1038/s41416-021-01301-4
- Definition and classification of cancer cachexia: an international consensus.Lancet Oncol. 2011; 12: 489-495https://doi.org/10.1016/S1470-2045(10)70218-7
- Differentiating sarcopenia and cachexia among patients with cancer.Nutr Clin Pract. 2017; 32: 30-39https://doi.org/10.1177/0884533616680354
- Development of the EORTC QLQ-CAX24, a questionnaire for cancer patients with cachexia.J Pain Symptom Manage. 2017; 53: 232-242https://doi.org/10.1016/j.jpainsymman.2016.09.010
PAL 13. Available at: https://www.nccn.org/professionals/physician_gls/pdf/palliative.pdf. Accessed: August 28, 2022.
- Management of Cancer Cachexia: ASCO guideline.J Clin Oncol. 2020; 38: 2438-2453https://doi.org/10.1200/JCO.20.00611
- Clinical oncology society of Australia: position statement on cancer-related malnutrition and sarcopenia.Nutr Diet. 2020; 77: 416-425https://doi.org/10.1111/1747-0080.12631
- Cachexia, dietetic consultation, and survival in patients with pancreatic and periampullary cancer: a multicenter cohort study.Cancer Med. 2020; 9: 9385-9395https://doi.org/10.1002/cam4.3556
- Defining barriers to implementation of nutritional advice in patients with cachexia.J Cachexia Sarcopenia Muscle. 2020; 11: 69-78https://doi.org/10.1002/jcsm.12490
- Nutrition interventions to treat low muscle mass in cancer.J Cachexia Sarcopenia Muscle. 2020; 11: 366-380https://doi.org/10.1002/jcsm.12525
- Integration of palliative, supportive, and nutritional care to alleviate eating-related distress among advanced cancer patients with cachexia and their family members.Crit Rev Oncol Hematol. 2019; 143: 117-123https://doi.org/10.1016/j.critrevonc.2019.08.006
- The psychosocial components of multimodal interventions offered to people with cancer cachexia: a scoping review.Asia Pac J Oncol Nurs. 2021; 8: 450-461https://doi.org/10.4103/apjon.apjon-219
- Cancer cachexia: rationale for the MENAC (Multimodal-Exercise, Nutrition and Anti-inflammatory medication for Cachexia) trial.BMJ Support Palliat Care. 2018; 8: 258-265https://doi.org/10.1136/bmjspcare-2017-001440
- Diagnosing sarcopenia at the point of imaging care: analysis of clinical, functional, and opportunistic CT metrics.Skeletal Radiol. 2021; 50: 543-550https://doi.org/10.1007/s00256-020-03576-9
- Sarcopenia and sarcopenic obesity are significantly associated with poorer overall survival in patients with pancreatic cancer: systematic review and meta-analysis.Int J Surg. 2018; 59: 19-26https://doi.org/10.1016/j.ijsu.2018.09.014
- A review of physical activity in pancreatic ductal adenocarcinoma: epidemiology, intervention, animal models, and clinical trials.Pancreatology. 2022; 22: 98-111https://doi.org/10.1016/j.pan.2021.10.004
- A multicenter, open-label, single-arm study of anamorelin (ONO-7643) in patients with cancer cachexia and low body mass index.Cancer. 2022; 128: 2025-2035https://doi.org/10.1002/cncr.34154
- Should omega-3 fatty acids be used for adjuvant treatment of cancer cachexia?.Clin Nutr ESPEN. 2018; 25: 18-25https://doi.org/10.1016/j.clnesp.2018.02.006
- Cannabinoid interventions for improving cachexia outcomes in cancer: a systematic review and meta-analysis.J Cachexia Sarcopenia Muscle. 2022; 13: 23-41https://doi.org/10.1002/jcsm.12861
- Review of the effects and safety of traditional Chinese medicine in the treatment of cancer cachexia.Asia Pac J Oncol Nurs. 2021; 8: 471-486https://doi.org/10.4103/apjon.apjon-2130
- Pancreatic carcinoma is associated with delayed gastric emptying.Dig Dis Sci. 1986; 31: 265-267https://doi.org/10.1007/BF01318117
- Gastroparesis: definitions and diagnosis.Gastroenterol Clin North Am. 2015; 44: 1-7https://doi.org/10.1016/j.gtc.2014.11.001
- Diagnostic and therapeutic approach to pancreatic cancer-associated gastroparesis: literature review and our experience.Dig Dis Sci. 2009; 54: 401-405https://doi.org/10.1007/s10620-008-0354-3
- Mirtazapine for symptom control in refractory gastroparesis.Drug Des Devel Ther. 2017; 11: 1035-1041https://doi.org/10.2147/DDDT.S125743
- Effect of mirtazapine on gastric emptying in patients with cancer-associated anorexia.Indian J Palliat Care. 2017; 23: 335-337https://doi.org/10.4103/IJPC.IJPC_17_17
- Symptom burden and lived experiences of patients, caregivers and healthcare professionals on the management of malignant bowel obstruction: a qualitative systematic review.Palliat Med. 2022; 36: 895-911https://doi.org/10.1177/02692163221081331
- Management of cancer-associated intestinal obstruction in the final year of life.J Palliat Care. 2020; 35: 84-92https://doi.org/10.1177/0825859719861935
- Illness understanding, prognostic awareness, and end-of-life care in patients with gi cancer and malignant bowel obstruction with drainage percutaneous endoscopic gastrostomy.JCO Oncol Pract. 2021; 17: e186-e193https://doi.org/10.1200/OP.20.00035
- Gaps in patient-physician communication at the time of malignant bowel obstruction from recurrent gynecologic cancer: a qualitative study.Support Care Cancer. 2022; 30: 367-376https://doi.org/10.1007/s00520-021-06441-0
- Palliative gastrostomy in the setting of voluminous ascites.J Palliat Med. 2014; 17: 811-821https://doi.org/10.1089/jpm.2013.0397
Siddappa PK, Hawa F, Prokop LJ, et al. Endoscopic pancreatic duct stenting for pain palliation in selected pancreatic cancer patients: a systematic review and meta-analysis. Gastroenterol Rep (Oxf) 2021;9:105-14. doi: 10.1093/gastro/goab001.
- Symptom relief and quality of life after stenting for malignant bile duct obstruction.Gut. 1994; 35: 467-470https://doi.org/10.1136/gut.35.4.467
- Effect of endoscopic stenting of malignant bile duct obstruction on quality of life.J Clin Gastroenterol. 2013; 47: 526-531https://doi.org/10.1097/MCG.0b013e318272440e
- Patient-reported experience measure in pancreatobiliary endoscopy: a systematic review to highlight areas for improvement.Eur J Gastroenterol Hepatol. 2021; 33: 832-838https://doi.org/10.1097/MEG.0000000000001957
- Malignant bowel obstruction.J Surg Oncol. 2019; 120: 74-77https://doi.org/10.1002/jso.25451
- Palliative therapy in pancreatic cancer-palliative surgery.Transl Gastroenterol Hepatol. 2019; 4: 28https://doi.org/10.21037/tgh.2019.04.03
PAL 20. Available at: https://www.nccn.org/professionals/physician_gls/pdf/palliative.pdf. Accessed: August 28, 2022.
- Pancreatic cancer and supportive care–pancreatic exocrine insufficiency negatively impacts on quality of life.Support Care Cancer. 2013; 21: 1835-1841https://doi.org/10.1007/s00520-013-1729-3
- Introduction and practical approach to exocrine pancreatic insufficiency for the practicing clinician.Int J Clin Pract. 2018; 72: e13066https://doi.org/10.1111/ijcp.13066
- Pancreatic exocrine insufficiency in patients with pancreatic or periampullary cancer: a systematic review.Pancreas. 2016; 45: 325-330https://doi.org/10.1097/MPA.0000000000000473
- Pancreatic exocrine insufficiency in pancreatic cancer: a review of the literature.Dig Liver Dis. 2015; 47: 1013-1020https://doi.org/10.1016/j.dld.2015.06.015
- Diagnostic performance of measurement of fecal elastase-1 in detection of exocrine pancreatic insufficiency: systematic review and meta-analysis.Clin Gastroenterol Hepatol. 2018; 16: 1220-1228https://doi.org/10.1016/j.cgh.2018.01.027
- Expert opinion on management of pancreatic exocrine insufficiency in pancreatic cancer.ESMO Open. 2022; 7100386https://doi.org/10.1016/j.esmoop.2022.100386
- Pancreatic enzyme replacement therapy for patients diagnosed with pancreaticobiliary cancer: validation of an algorithm for dose escalation and management.Pancreas. 2021; 50: 1254-1259https://doi.org/10.1097/MPA.0000000000001906
- Financial burden of drugs prescribed for cancer-associated symptoms.JCO Oncol Pract. 2022; 18: 140-147https://doi.org/10.1200/OP.21.00466
- Frequency of appropriate use of pancreatic enzyme replacement therapy and symptomatic response in pancreatic cancer patients.Pancreas. 2019; 48: 780-786https://doi.org/10.1097/MPA.0000000000001330
- The impact of pancreatic enzyme replacement therapy on patients with advanced pancreatic adenocarcinoma: a systematic review and narrative synthesis.Pancreas. 2022; 51: 405-414https://doi.org/10.1097/MPA.0000000000002049
- Synopsis of a clinical practice guideline for pancreatic ductal adenocarcinoma with peritoneal dissemination in Japan; Japan Peritoneal malignancy study group.J Hepatobiliary Pancreat Sci. 2022; 29: 600-608https://doi.org/10.1002/jhbp.1085
- A palliative approach to management of peritoneal carcinomatosis and malignant ascites.Surg Oncol Clin N Am. 2021; 30: 475-490https://doi.org/10.1016/j.soc.2021.02.004
- Anxiety, depression and quality of life in people with pancreatic cancer and their carers.Pancreatology. 2017; 17: 321-327https://doi.org/10.1016/j.pan.2017.01.008
- Caring experiences of family caregivers of patients with pancreatic cancer: an integrative literature review.Support Care Cancer. 2022; 30: 3691-3700https://doi.org/10.1007/s00520-021-06793-7
- The self-efficacy of family caregivers for helping cancer patients manage pain at end-of-life.Pain. 2003; 103: 157-162https://doi.org/10.1016/s0304-3959(02)00448-7
- Coping in patients with pancreatic cancer: a scoping review and narrative synthesis.BMJ Support Palliat Care. 2021; https://doi.org/10.1136/bmjspcare-2021-003266
- Diet and nutrition information on nine national cancer organisation websites: a critical review.Eur J Cancer Care (Engl). 2020; 29: e13280https://doi.org/10.1111/ecc.13280
- Future directions in preclinical and translational cancer neuroscience research.Nat Cancer. 2021; 1: 1027-1031https://doi.org/10.1038/s43018-020-00146-9
- Therapeutic avenues for cancer neuroscience: translational frontiers and clinical opportunities.Lancet Oncol. 2022; 23: e62-e74https://doi.org/10.1016/S1470-2045(21)00596-9